DVOŘÁKOVÁ, Marcela, VALTEROVÁ, Irena, ŠAMAN, David, VANĚK, Tomáš. Biotransformation of (1S)-2-Carene and (1S)-3-Carene by Picea abies Suspension Culture. Molecules. 2011, 16(12), 10541-10555. ISSN 1420-3049. E-ISSN 1420-3049

Biotransformation of (1S)-2-carene and (1S)-3-carene by Picea abies suspension culture led to the formation of oxygenated products. (1S)-2-Carene was transformed slowly and the final product was identified as (1S)-2-caren-4-one. On the other hand, the transformation of (1S)-3-carene was rapid and finally led to the formation of (1S)-3-caren-5-one and (1S)-2-caren-4-one as equally abundant major products. The time-course of the reaction indicates that some products abundant at the beginning of the reaction (e.g. (1S,3S,4R)-3,4-epoxycarane and (1R)-p-mentha-1(7),2-dien-8-ol) were consumed by a subsequent transformations. Thus, a precise selection of the biotransformation time may be used for a production of specific compounds.